Clinical trials

5

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Effects of Aphasia Identification Cards on Service Workers' Comprehension of People With Aphasia

The goal of this clinical trial is to learn whether healthy volunteers are more successful at understanding people with aphasia if they have first viewed an aphasia identification (ID) card. The main questions this study aims to answer are: * Does viewing an aphasia ID card improve healthy volunteers' understanding of the language errors made by people with aphasia? * Does viewing an aphasia ID card improve healthy volunteers' understanding of people with aphasia who make long pauses in their speech? Researchers will compare aphasia ID cards to a control condition (no ID card) to see whether aphasia ID cards improve healthy volunteers' understanding. Healthy volunteers will visit the study site for a single session (about 2 hours long). During the session they will: * Complete brief tests of their vision, hearing and thinking * Listen to sentences produced by a speaker with aphasia while their eye movements are recorded * Complete a survey about the experience of listening to the speaker with aphasia

Participants needed: 160
Trial details
Age: 18-59Biological sex: AllType: InterventionalSponsor: University of Massachusetts, AmherstUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Adult age 18-59 [+4]

Language disorder [+3]

Status: Recruiting

Burning Mouth Syndrome: Symptoms and Management

This research study aims to evaluate how an oral cooling spray, currently a commercial dietary supplement, impacts symptoms associated with burning mouth syndrome (BMS). This study will examine symptoms, frequency, and severity, along with other related side effects of BMS on food intake, enjoyment, and quality of life.

Participants needed: 50
Trial details
Phase: Early Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: University of Massachusetts, AmherstUpdated: Jun 11, 2025Locations: 1
Eligibility criteria

Have buring mouth syndrome or experience oral burn [+8]

Have recently undergone dental treatment in the last three months or have plans... [+1]

Status: Not yet recruiting

Promoting Maintenance of Change Following Brief Intervention for Alcohol Use

All students who enroll in the study will receive an efficacious counselor-delivered brief motivational intervention. The intervention is based in principles of motivational interviewing. Students complete a baseline assessment on their alcohol use and alcohol-related consequences. During the hour-long session, the counselor uses information from the baseline assessment to compare the student's level of alcohol consumption to that of peers at the same university, discuss choices that may lead to experiencing negative consequences, and provide opportunities for the student to set goals for risk reduction. This study will develop and pilot a maintenance enhancement intervention. The intervention is expected to consist of four components, for example: (1) Student participants may learn to use techniques based in mindfulness to cope with negative emotions. (2) Student participants may identify barriers to reducing their alcohol use and identify protective strategies for navigating those barriers. (3) Student participants may be presented with narratives from other students who successfully resumed moderate drinking after a heavy drinking episode. Students may also be prompted to identify alcohol free activities that they enjoy and can engage in after experiencing a heavy drinking episode. (4) Parents may also receive a handbook encouraging communication with their student about alcohol use.

Participants needed: 160
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Massachusetts, AmherstUpdated: Apr 15, 2025
Eligibility criteria

Currently enrolled student at the University of Massachusetts Amherst [+3]

Status: Recruiting

Sleep-dependent Learning in Aging

The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.

Participants needed: 584
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: University of Massachusetts, AmherstUpdated: Apr 3, 2025Locations: 1
Eligibility criteria

Age 18-80 yrs [+2]

Past diagnosis of any sleep disorder or evidence of a sleep disorder as assessed... [+16]

Status: Recruiting

The Function of Biphasic Sleep in Infants

This study is designed to investigate developmental changes in naps and nap function on memory from 9 to 15 months of age. Memory is measured by a task in which the experimenter interacts with a toy and the measure of memory is whether the child imitates that action when given the toy. Sleep is assessed with a watch that detects motion which provides an estimate of sleep and a set of electrodes placed on the head that measures brain activity during sleep. Infants are recruited at 9 months and sleep and memory are measured again 3- and 6-months later. At each visit, memory is tested before and after a nap (either the morning or afternoon nap) and naps are recorded with the sleep electrodes.

Participants needed: 100
Trial details
Age: 9-15Biological sex: AllType: InterventionalSponsor: University of Massachusetts, AmherstUpdated: May 8, 2024Locations: 1
Eligibility criteria

9 months at the time of enrollment [+2]

born premature (<36 weeks gestational age) [+8]