Clinical trials

9

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors

This is a study for people with locally advanced or metastatic cancer for whom previous treatment was not successful. Adults aged 18 and over with advanced cancer with Epidermal Growth Factor Receptor (EGFR) overexpressing can join the study. The purpose of this study is to find out whether a medicine called YH32364 helps people with locally advanced or metastatic cancers with EGFR overexpression.

Participants needed: 80
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Jun 10, 2026Locations: 4
Eligibility criteria

Must sign an informed consent form (ICF) prior to any study specific procedures [+12]

Known uncontrolled central nervous system (CNS) metastases, spinal cord compress... [+16]

Status: Recruiting

Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

This first-in-human study will be counducted to evaluate the safety, tolerability, pharmacokinetics (PK) and anti-tumor activity of YH32367 in Patients with HER2-Positive Locally Advanced or Metastatic Solid Tumors.

Participants needed: 147
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Jun 11, 2026Locations: 19
Eligibility criteria

Pathologically confirmed HER2-positive [+5]

Uncontrolled central nervous system (CNS) metastases [+12]

Status: Recruiting

Bioequivalence (BE) Study Between YHP2511 and YHP2511A in Healthy Volunteers

A randomized, open-label, single-dose, 2-sequence, 2-period, crossover clinical trial to investigate the bioequivalence between YHP2511 and YHP2511A in healthy volunteers

Participants needed: 60
Trial details
Phase: Phase 1Age: 19-55Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Jun 2, 2026Locations: 1
Eligibility criteria

Adults aged 19 to 55 years at the time of screening visit. [+3]

Those who have participated in a bioequivalence study or other clinical trials a... [+2]

Status: Not yet recruiting

Bioequivalence Study Between YHP2508C and YHR2603 in Healthy Subjects

An open-label, randomized, fasting, single-dose, oral administration, 2-sequence, 4-period, replicate crossover study to evaluate bioequivalence between YHP2508C and YHR2603 in healthy subjects

Participants needed: 44
Trial details
Phase: Phase 1Age: 19-54Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: May 13, 2026
Eligibility criteria

BMI 18-30 kg/m2 [+1]

Those who have participated in a bioequivalence study or other clinical trials a... [+2]

Status: Recruiting

Phase 2 Study of Lesigercept in Adult Patients With Chronic Spontaneous Urticaria Who Are Inadequately Controlled by H1-Antihistamines

This study aims to evaluate the efficacy and safety of lesigercept in approximately 150 participants with CSU. By enrolling participants with an inadequate response to H1-antihistamines, including those previously treated with omalizumab, this study is expected to provide evidence for the clinical utility of lesigercept and to further characterize its benefit-risk profile in the target participant population.

Participants needed: 150
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Apr 15, 2026Locations: 30
Eligibility criteria

Chronic spontaneous urticaria for ≥6 months, uncontrolled on 2nd-generation H1-a... [+3]

Any medical or lab findings suggesting risk of worsening co-existing conditions... [+4]

Status: Recruiting

A First-in-Human, Single- and Multiple-Ascending Dose Study of YH35995 in Healthy Adult Male Participants

This is a randomized, double-blind, first-in-human study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of YH35995

Participants needed: 86
Trial details
Phase: Phase 1Age: 19-45Biological sex: MaleType: InterventionalSponsor: Yuhan CorporationUpdated: Nov 21, 2025Locations: 1
Eligibility criteria

Male between the ages of 19 and 45 at the time of providing written consent [+2]

Participation in a bioequivalence trial or any other clinical trials within 6 mo... [+2]

Status: Recruiting

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

The goal of this YH42946-101 is to evaluate the safety, Tolerability, Pharmacokinetics and anti-tumor activity of YH42946 in patients with locally advanced of metastatic solid tumors with HER2 aberration and EGFR exon 20 insertions.

Participants needed: 161
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Nov 4, 2025Locations: 8
Eligibility criteria

ECOG performance status 0 or 1 [+10]

Patient with symptomatic or progressive brain metastases [+13]

Status: Recruiting

Clinical Trial to Evaluate the Safety and Efficacy of NTCB02-1 in Patients Who Require Parenteral Nutrition

A Randomized, Open-labeled, Multi-center, Active-controlled, Parallel-group Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of NTCB02-1 versus NTCB-C in patients who require parenteral nutrition

Participants needed: 60
Trial details
Phase: Phase 3Age: 19+Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Jan 7, 2025Locations: 5
Eligibility criteria

Those who are 19 years old or older at the screening visit [+2]

Patients are expected difficult to survive more than 3 days [+4]

Status: Recruiting

An Observational, Prospective Study to Assess the Efficacy and Safety of Adalloce in Patients With RA and AS

This Study is to Assess the Efficacy and Safety of Adalloce in Patients With Rheumatoid Arthritis and Ankylosing Spondylitis, An Observational, Prospective Study

Participants needed: 1,000
Trial details
Age: 19-74Biological sex: AllType: ObservationalSponsor: Yuhan CorporationUpdated: May 9, 2023Locations: 1
Eligibility criteria

Men and women between the ages of over 19 and under 75 at the time of consent [+4]

Patients with hypersensitivity to this drug or its components [+5]