Comparison of Sevoflurane and Propofol on ANI

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorPusan National University Yangsan Hospital

About this trial

The goal of this clinical trial is to compare the effect of sevoflurane and propofol on analgesia nociception index(ANI) in patients undergoing general anesthesia. The main question it aims to answer is whether propofol anesthesia results in lesser ANI change to a nociceptive stimulation compared to sevoflurane.

Eligibility criteria

Qualifiers

American society of anesthesiologists physical status class I or II

Disqualifiers

history of drugs that can affect the central nervous system and autonomic nervous system, such as anticholinergics, betablockers, antidepressants..etc.

history of allergic reaction to sevoflurane and/or propofol

history of and/or family history of malignant hyperthermia

neurodegenerative disorder

Trial design

Treatments tested in this trial

  • propofol
  • Sevoflurane

Treatment groups

30 Participants
are divided into 2 treatment groups

Locations

This trial has no locations