Comparison of Sevoflurane and Propofol on ANI
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorPusan National University Yangsan Hospital
The goal of this clinical trial is to compare the effect of sevoflurane and propofol on analgesia nociception index(ANI) in patients undergoing general anesthesia. The main question it aims to answer is whether propofol anesthesia results in lesser ANI change to a nociceptive stimulation compared to sevoflurane.
American society of anesthesiologists physical status class I or II
history of drugs that can affect the central nervous system and autonomic nervous system, such as anticholinergics, betablockers, antidepressants..etc.
history of allergic reaction to sevoflurane and/or propofol
history of and/or family history of malignant hyperthermia
neurodegenerative disorder