Early Neurovascular Adaptations in Aging Women

Trial statusRecruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexFemale
Age18-70
SponsorUniversity of Missouri-Columbia

About this trial

Our goal is to enhance our understanding of early vascular adaptations in aging women with an emphasis on the sympathetic nervous system.

Eligibility criteria

Qualifiers

Assigned female at birth (AFAB)

18-70 years of age

Disqualifiers

Assigned male at birth (AMAB)

Pregnancy, breastfeeding

Body mass index ≥30 kg/m2

Taking medications known to affect metabolic, autonomic, and/or respiratory function

Trial design

Treatments tested in this trial

  • Norepinephrine
  • Isoproterenol
  • Acetylcholine
  • Nitroprusside
  • Estrogen

Treatment groups

64 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Missouri-Columbia

Lead sponsor

American Heart Association

Collaborator