Effect of Prebiotics in Saudi Adults With Type 2 Diabetes
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age45-60
SponsorPrincess Nourah Bint Abdulrahman University
About this trial
This study will explore how a natural food ingredient called oligofructose affects blood glucose levels, lipid profiles, inflammation biomarkers, and gut bacteria in Saudi adults with type 2 diabetes. Oligofructose is a type of dietary fiber found in foods such as onions, garlic, and bananas. It is known to help the growth of "good" bacteria in the intestine, which may improve digestion and metabolism.
A total of 100 adults (50 with type 2 diabetes and 50 without diabetes) will take part in this research. Participants will be randomly assigned to receive either oligofructose or a placebo twice daily for 12 weeks. Blood tests will be done at the beginning and at weeks 4, 8, and 12 to check changes in blood glucose, lipid profiles, and inflammation.
The goal of this study is to find out whether adding oligofructose to the diet can help people with diabetes improve their blood glucose control, reduce inflammation, and support a healthier balance of gut bacteria.
Eligibility criteria
Qualifiers
Saudi, both males and females.
Aged between 45-60 years old
BMI between 25 - 30 kg/m2
No antibiotic use for the last six months
Disqualifiers
Patients with Type 1 diabetes.
Pregnant & breastfeeding females.
Any serious disease such as renal or hepatic disease, thyroid functions, coeliac disease, or the presence of gastroparesis.
Use of weight-loss treatments within 3 months before inclusion
Trial design
Treatments tested in this trial
- oligofructose
- Maltodextrin (Placebo)
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov