Objectively Diagnose and Monitor Treatment of Light Sensitivity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorRandy Kardon
About this trial
The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses, retinal electrical responses and autonomic nerve responses to light.
Eligibility criteria
Qualifiers
Healthy individuals with normal eye exam in the previous year
Age 18-80
Disqualifiers
History of eye or systemic disorder that affect the retina, optic nerve, visual pathway, or pupil defect: including glaucoma, optic neuropathy, or retinal disease, diabetes and/or hypertension that are not well controlled, history of head trauma, concussion, or TBI, history of cervical or spinal injury/surgery
Medications or eyedrops that would confound measuring the pupil light reflex and EMG: including topical autonomic drugs that could influence pupil size, ocular pharmacologic agents, sedative agents (e.g. benzodiazepines or barbiturates), opioid narcotics
Must not be light sensitive or get migraine headaches
Age 18-80
Trial design
Treatments tested in this trial
- Pupillography
- Ocular Coherence Tomography (OCT)
- Wrist-watch sensor device
- Videography
- Electrophysiology
Treatment groups
120 Participants
are divided into 5 treatment groupsSponsors and collaborators
Randy Kardon
Lead sponsor
University of Iowa
Sponsor institution
Source ClinicalTrials.gov