This multicenter randomized controlled trial compare two transfusion strategies of red blood cells transfusion in patients supported by veno-arterial extracorporeal membrane oxygenation for refractory cardiogenic shock.
An individualized transfusion strategy based on ScVO2 level, is compared to a conventionnal strategy based on predefined hemoglobin threshold. The primary endpoint is the consumption of packed red blod cells, secondary endpoints are subgroup analysis, mortality, morbidity, and cost-effectiveness
Age of 18 and older,
supported by peripheral VA-ECMO
for cardiogenic shock
Life expentency >90 days
Pregnancy,
Lack of health insurance,
Opposition to blood transfusion,
Known congenital hemoglobin disease or disorder,
University Hospital, Lille
Lead sponsor
Amiens University Hospital
Collaborator
University Hospital, Caen
Collaborator
University Hospital, Rouen
Collaborator
Centre Hospitalier Universitaire Dijon
Collaborator
Centre Hospitalier de Lens
Collaborator