Study SOLACE SEPSIS
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-90
SponsorUniversity Hospital Pilsen
About this trial
A Pilot, Randomized, Double-Blinded, Controlled Study of Hemodynamic and Acid Base Effects of 0.5M Sodium Lactate and 3% Saline Solutions in Septic Shock Patients
Eligibility criteria
Qualifiers
Age criteria: 18 - 90 years
acute change in total SOFA score ≥ 2 due to infection
use of vasopressor drug to maintain target mean arterial pressure ≥ 65 mmHg
blood lactate level ≥ 2 mmol/L within last 24 hours
Disqualifiers
Poor transthoracic echo windows
Actual body weight > 160 kg
Hypernatremia: [Na] > 150 mEq/L
Cardiac tamponade
Trial design
Treatments tested in this trial
- Sodium Lactate
- 3% NaCl
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov