Weaning Approaches for Vasopressin in Sepsis
ConditionSeptic Shock
Trial statusRecruiting
Trial phasePhase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorHospital Nossa Senhora da Conceicao
About this trial
In this study, we aim to evaluate the incidence of hypotension during vasopressin weaning by comparing two methods - titrated reduction versus abrupt withdrawal - through the conduct of a randomized clinical trial.
Eligibility criteria
Qualifiers
Age over 18 years
Admitted to the Intensive Care Unit
Patients with vasopressor dependent sepsis
Receiving combined norepinephrine and vasopressin therapy
Disqualifiers
Withdrawal/reduction of vasopressin related to a plan of treatment limitation or palliative care
Withdrawal/reduction of vasopressin associated with the initiation of adrenaline or any other vasopressor
Trial design
Treatments tested in this trial
- Titrated weaning of vasopressin.
- Abrupt weaning of vasopressin.
Treatment groups
82 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov