About this trial
Elective laparoscopic cholecystectomy may lead to perioperative atelectasis due to pneumoperitoneum-related diaphragmatic elevation and impaired respiratory mechanics. Lung ultrasound (LUS) provides a noninvasive bedside method for evaluating perioperative aeration loss. This prospective randomized controlled study aims to compare the effects of low-pressure (10 mmHg) and standard-pressure (14 mmHg) pneumoperitoneum on perioperative atelectasis assessed by LUS in patients undergoing laparoscopic cholecystectomy under general anesthesia. Changes in LUS scores, respiratory mechanics, oxygenation, and postoperative clinical outcomes will also be evaluated.
Eligibility criteria
Qualifiers
Patients aged between 18 and 65 years
ASA physical status I-II
Scheduled for elective laparoscopic cholecystectomy under general anesthesia
Body mass index (BMI) <30 kg/m²
Disqualifiers
Chronic pulmonary disease
Recent respiratory tract infection
Thoracic deformity or previous thoracic surgery
Preoperative pulmonary pathology
Trial design
Treatments tested in this trial
- 10 mmHg Pneumoperitoneum
- 14 mmHg Pneumoperitoneum
Treatment groups
Sponsors and collaborators
Engin Çetin
Lead sponsor
Kocaeli City Hospital
Sponsor institution