The primary aim of the study is to determine the proportion of individuals receiving beta-lactam antibiotics at Imperial College Healthcare NHS Trust in whom drug concentration targets are achieved.
Under follow-up for management of infection at Imperial College NHS Trust
Received a beta-lactam antibiotic within the last 48 hours (or are planned to start imminently).
Delirium which may be caused or exacerbated by having an infection.
Suspected/confirmed central nervous system infection.
Less than 18 years of age
Severe anaemia (Hb < 70g/l)
Platelets < 50x10^9/l, INR >1.5 or other known blood clotting impairment
Patient with terminal diagnosis receiving palliative care input who may experience distress if approached for this study.