This study will be conducted to evaluate the effects of different anesthetic modalities \[sevoflurane with or without intraoperative lidocaine infusion and Propofol total intravenous anesthesia (TIVA)\] on intracranial pressure (ICP) and cerebral oxygenation assessed by non-invasive methods during laparoscopic hysterectomy (LH).
Age from 18 to 65 years.
American Society of Anesthesiologists (ASA) physical status I and Ⅱ.
Body mass index (BMI) ≤35.
Females scheduled for laparoscopic hysterectomy.
Patients' refusal to participate in the study.
Hypersensitivity and allergy to drugs of the study.
Contraindication for optic nerve sheath diameter assessment. E.g., patient with pre-existing ophthalmic diseases, a history of ophthalmic surgery
Any central nervous system or cardiovascular disease, severe hepatic or renal impairment