About this trial
This study aims to evaluate the effects of fully immersive virtual reality (VR) applications on upper extremity (UE) functions in individuals diagnosed with Duchenne Muscular Dystrophy (DMD). DMD is a progressive neuromuscular disorder that leads to muscle weakness and loss of function, including the upper limbs, which are essential for daily activities and independence.
In this randomized controlled trial, 36 participants with DMD will be divided into two groups: a control group receiving conventional physiotherapy and an intervention group receiving the same physiotherapy program (excluding upper extremity exercises) combined with VR-based exercises. The VR games will be designed specifically to improve shoulder, elbow, wrist, and hand functions and will be delivered using Meta Quest 3 headsets with hand-tracking capabilities.
Both groups will receive therapy twice a week for 8 weeks. Assessments will be conducted before and after the intervention, and at follow-up, using validated tools to measure UE function, grip strength, fine motor skills, trunk control, fatigue, quality of life, and participation in daily activities.
The study aims to explore innovative rehabilitation strategies for DMD and contribute to improving the independence and quality of life of affected individuals.
Eligibility criteria
Qualifiers
Clinical diagnosis of Duchenne Muscular Dystrophy (DMD)
Age ≥ 7 years
Ambulatory or non-ambulatory status (both are eligible)
Ability to follow movement instructions
Disqualifiers
Presence of any neurological diagnosis other than DMD
Cognitive, behavioral, or communication impairments that limit participation
Systemic illness or condition interfering with participation
Severe visual impairments incompatible with VR headset use
Trial design
Treatments tested in this trial
- Virtual Reality + Conventional Physiotherapy
- Conventional Physiotherapy
- Formative Usability Evaluation of the VR Rehabilitation Platform
Treatment groups
Sponsors and collaborators
Istanbul University
Lead sponsor
Istanbul University - Cerrahpasa
Sponsor institution