Neck Pain Musculoskeletal

11

Review clinical trials related to Neck Pain Musculoskeletal. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Mobilization Techniques for Nonspecific Neck Pain: Effects on Cervical Endurance and Function

This clinical study investigates the comparative effects of two manual therapy mobilization techniques, Positional Release Technique (PRT) and Instrument-Assisted Soft Tissue Mobilization (İASTM), on cervical muscle endurance and functional performance in individuals with nonspecific neck pain. Nonspecific neck pain is a common musculoskeletal condition among office workers and students, often associated with poor posture, prolonged sitting, and repetitive strain. It leads to reduced muscle endurance, impaired functional capacity, and decreased quality of life. Early and effective management strategies are essential to prevent chronicity and disability. A total of 51 participants will be recruited and randomly assigned into three groups: Group 1 will receive PRT combined with a standardized home exercise program, Group 2 will receive İASTM combined with the same home exercise program, and Group 3 will serve as the control group receiving only conventional home exercise. The interventions will be delivered over a period of 4 weeks, with three sessions per week, under the supervision of trained physiotherapists. The home exercise program includes stretching, strengthening, and posture correction exercises designed to support cervical spine health. The primary outcomes of the study are cervical muscle endurance and functional performance, measured using validated clinical tests. Secondary outcomes include pain intensity assessed by the Visual Analog Scale (VAS), functional disability measured by the Neck Disability Index (NDI), health-related quality of life assessed by the SF-12 questionnaire, and work-related performance indicators. Assessments will be conducted at baseline and after 4 weeks of intervention. Randomization and blinding procedures will be applied to minimize bias, and standardized protocols will ensure consistency across groups. The main objective of this study is to determine whether the early application of PRT or İASTM, in combination with home exercise, provides superior improvements in cervical muscle endurance, pain reduction, and functional outcomes compared to exercise alone. By comparing these two mobilization techniques, the study aims to contribute evidence-based knowledge to physiotherapy practice and guide clinicians in selecting effective manual therapy approaches for nonspecific neck pain. The findings are expected to support clinical decision-making, improve patient care, and enhance rehabilitation strategies for individuals suffering from neck pain in occupational and daily life contexts.

Participants needed: 51
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: Istanbul University - CerrahpasaUpdated: May 28, 2026Locations: 1
Eligibility criteria

Healthy individuals aged 18-40 years [+3]

History of neck trauma, surgery, or any cardiovascular, metabolic, neurological,... [+3]

Status: Recruiting

Osteopathic Manipulative Treatment vs Physiotherapy in Cervicocranial Dysfunction

This study aims to compare the effects of osteopathic manipulative treatment and standard physiotherapy in patients with cervicocranial dysfunction. The study will evaluate outcomes including dizziness, headache impact, neck disability, and psychological stress. Participants will be randomly assigned to one of two groups: osteopathic treatment or standard physiotherapy. The interventions will be applied over a defined treatment period, and outcomes will be measured before and after the intervention. The purpose of this study is to determine which approach is more effective in improving symptoms and functional outcomes in patients with cervicocranial dysfunction.

Participants needed: 50
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Burim PeliUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Age between 18 and 65 years. [+6]

Clinically confirmed vestibular disorders. [+6]

Status: Recruiting

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief

Neck pain is a common issue that can lead to long-term disability and lost work time for many individuals. Despite numerous studies, finding effective treatment strategies has been challenging. One possible reason for this is that treatments may not have been tested on the specific groups of people who would benefit most. A method was developed to identify people with neck pain who are likely to see significant improvements from a manipulation technique used by physical therapists, called cervical spine thrust joint manipulation. The investigators believe that patients identified as likely responders to cervical spine manipulation will show greater improvements in disability. The investigators aim to test whether this method works with different patients and therapists across the country through a multicenter randomized clinical trial. In this study, 160 patients with primary complaints of neck pain will be enrolled from 9 clinical sites. Designed with stringent criteria for inclusion, this study is a testament to our commitment to participant safety and the effectiveness of the treatment. Participants will be randomly assigned to one of two groups: (1) one group will receive 2 sessions of cervical spine manipulation followed by 3 sessions of exercise, and (2) the other group will receive 2 sessions of gentle hands-on treatment followed by 3 sessions of exercise. The primary goal is to measure changes in disability 4 weeks after starting treatment, with follow-ups after one week, 4 weeks, 3 months, and 6 months to assess both immediate and long-term effects. By providing crucial data on the reliability of our method in identifying patients who will benefit most from cervical spine manipulation, this study has the potential to significantly enhance decision-making leading to rapid improvement. Results from this study will provide clearer guidelines on the optimal use of cervical spine manipulation, potentially revolutionizing the way patients recover from neck pain.

Participants needed: 160
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Baylor UniversityUpdated: Apr 14, 2026Locations: 4
Eligibility criteria

Ages 18 to 70 [+3]

History of whiplash injury within the past 6 weeks [+14]

Status: Not yet recruiting

Neck Musculoskeletal Symptoms Among Turkish Endodontists

This observational study aims to evaluate the prevalence, severity, and characteristics of neck musculoskeletal symptoms among Turkish endodontists. Endodontists are exposed to prolonged static postures and repetitive movements during clinical procedures, which may increase the risk of neck-related disorders. Participants will be asked to complete questionnaires regarding demographic characteristics, occupational factors, ergonomic conditions, and neck pain. In addition, physical assessments including cervical range of motion, muscle strength, endurance, posture, and proprioception will be performed using validated measurement tools. The study also aims to identify factors associated with neck pain, such as working conditions, posture, and clinical experience. The findings may help improve preventive strategies, ergonomic recommendations, and rehabilitation approaches for dental professionals.

Participants needed: 120
Trial details
Age: 25-65Biological sex: AllType: ObservationalSponsor: Atlas UniversityUpdated: Apr 8, 2026Locations: 1
Eligibility criteria

Aged 25 to 65 years [+3]

History of cervical spine surgery within the last 3 months [+6]

Status: Not yet recruiting

Effect of Body Mind Exercises and Specific Neck Exercises in Chronic Mechanical Neck Pain

To investigate the effect of body mind exercise and specific neck exercises in chronic mechanical neck pain on neck pain severity, functional disability, neck flexion range of motion, isometric neck muscle strength and quality of life.

Participants needed: 80
Trial details
Age: 50-65Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Adults aged between 50-65 years [+2]

History of cervical surgery [+3]

Status: Not yet recruiting

The Effectiveness of Dynamic Neuromuscular Stabilization (DNS) Exercises Compared to Localized Exercises and Standard Care on Pain Intensity, Neck Dysfunction, and Upper Cervical Range of Motion in Patients With Chronic Neck Pain: A Pilot Randomized Controlled Trial (RCT)

Many people experience long-lasting neck pain, which can affect daily life, work, and overall well-being. This study aims to find out which type of exercise program is most effective in reducing neck pain, improving neck movement, and making daily activities easier. What Is Being Studied?: The study compares three different types of treatment: DNS Exercises (Dynamic Neuromuscular Stabilization): Whole-body exercises focusing on posture, breathing, and core stability. Localized Neck Exercises: Targeted exercises for the neck and shoulder muscles. Standard Care: Usual physiotherapy treatment commonly provided in clinical practice. Study Procedures: Participants are randomly assigned to one of the three groups. Each participant receives individual exercise instruction from a physiotherapist. Participants are also given simple home exercises to perform on their own. The study lasts for about 12 weeks. What Will Be Measured?: At the beginning, during, and at the end of the study, the following will be assessed: Neck pain intensity (pain scale) Neck range of motion How much the pain affects daily life and activities Possible Benefits: Participants may experience: Less neck pain Improved neck mobility Better overall body awareness Even if not every participant notices improvement, taking part will help researchers improve future treatment options for chronic neck pain. Risks: No major risks are expected. All exercises are supervised by qualified physiotherapists and adjusted to each participant's abilities. Participation can be stopped at any time if discomfort or pain occurs. Voluntary Participation and Data Privacy: Participation is completely voluntary. All personal data will be kept confidential and analyzed anonymously for research purposes only. Participants may withdraw from the study at any time without any disadvantages.

Participants needed: 45
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Hochschule OsnabruckUpdated: Feb 9, 2026
Eligibility criteria

between 18 and 50 years of age. This ensures a homogeneous population that in-cl... [+3]

Cancer [+9]

Status: Not yet recruiting

Musical Mindfulness for Pain in the ED Waiting Room

Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain. However, with the current ongoing opioid epidemic, it is important to consider other methods, both pharmacologic and nonpharmacologic, of pain reduction. Jazz music specifically has been demonstrated to have therapeutic effects on pain that can be used to lower the quantity of opioids administered to patients. Non-pharmacological interventions in the emergency department for pain typically consist of splinting an injury, applying heat or cold, or various distractions following initial and sequential pain assessment. Pharmacological interventions for pain in the Emergency Department involve the administration of acetaminophen, muscle relaxers, topical anesthetics, opioids, to name a few. In the emergency department (ED), providers are increasingly hesitant to prescribe opioids over the past decade due to the current opioid epidemic, in which there is an increasing proportion of people that develop an addiction to opioids, including those that are prescribed to them for pain management.. While emergency medicine providers' decrease in opioid prescriptions pertains to their implementation of opioid-prescribing policies, little evidence has been found demonstrating a direct link in these policies to decreases in substance misuse. Consequently, providers find themselves needing to become ingenious in their approach to pain in patients through the integration of pharmacologic and non-pharmacologic mediums of analgesia. A recent randomized controlled trial (RCT) from Brigham and Women's Hospital in Boston sought to identify the qualitative responses from patients in the ED following the arbitrary distribution of either supervised or unsupervised music therapy over a time period of 4 hours. The initial results found that, generally speaking, music therapy may lower reported pain and anxiety scores. Furthermore, stronger results were identified in case subjects with higher initial reports of pain via a pain catastrophizing scale, implying that a higher baseline of pain results in more relief from music therapy. One shortcoming in the article is the lack of analysis with reported results and the biopsychosocial model of pain. Heavy emphasis is placed on the psychological and social components of pain in the Brigham and Women's article through the implementation of the Pain Catastrophizing Scale and Brief Pain Inventory scoring done during the RCT, but no focus on linked biological changes in the subjects through the music therapy intervention. The purpose of this study is to (i.) assess the effect of a video training about musical pain management followed by a 15-minute music listening intervention on self-reported pain scores in ED patients with neck and back pain. The investigators also aim to (ii.) evaluate patient satisfaction and emotional response following the intervention. Opioid medications are commonly used to reduce substantial pain, and music therapy has been found to reduce associated pain and anxiety in patients, then the use of music therapy could be an aid in medicine to reduce opioid intake. The investigators hypothesize that the usage of a training on musical pain management combined with a specified jazz musical intervention will produce a significantly lower measured pain score in comparison to a video on mindful pain management followed by the patient's choice of activities.

Participants needed: 60
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: University of California, IrvineUpdated: Feb 6, 2026Locations: 1
Eligibility criteria

- Age >= 18 years old and <=75 years old [+1]

Status: Not yet recruiting

Sleep Hygiene Plus Physiotherapy for Sleep and Disability in Chronic Neck Pain

This study investigates the effectiveness of a combined intervention that integrates sleep hygiene education with physiotherapy exercises in patients suffering from chronic neck pain. Chronic neck pain is often associated with both musculoskeletal dysfunction and secondary sleep disturbances, which in turn may exacerbate pain perception, fatigue, and disability. Traditional physiotherapy exercise programs focus primarily on improving cervical mobility, muscle strength, and postural control, but they do not typically address sleep-related problems that can hinder recovery. The intervention in this study consists of two main components: Physiotherapy Exercise Program - A structured regimen targeting cervical spine mobility, deep cervical flexor strengthening, scapular stabilization, and postural correction. These exercises aim to reduce pain, restore function, and improve overall physical performance. Sleep Hygiene Education - A structured educational module covering principles of healthy sleep habits, including maintaining consistent sleep-wake schedules, creating an optimal sleep environment, limiting stimulants before bedtime, and adopting relaxation strategies to promote better sleep initiation and maintenance. By combining these approaches, the intervention addresses not only the physical impairments associated with chronic neck pain but also the psychosocial and behavioral factors contributing to poor sleep quality. Outcome Measures: Primary Outcomes: Sleep quality, assessed using validated tools such as the Pittsburgh Sleep Quality Index (PSQI). Secondary Outcomes: Disability and functional limitations, measured by the Neck Disability Index (NDI), along with pain intensity assessed using a Visual Analog Scale (VAS). Fatigue will be assessed by fatigue inventory index Study Hypothesis: The combined intervention of sleep hygiene education and physiotherapy exercise will lead to greater improvements in sleep quality and reductions in disability and fatigue compared to physiotherapy exercise alone. Clinical Significance: If effective, this integrative approach may provide a cost-effective, non-pharmacological management strategy for patients with chronic neck pain, targeting both physical and behavioral contributors to their condition.

Participants needed: 120
Trial details
Age: 25-55Biological sex: AllType: InterventionalSponsor: Al-Azhar UniversityUpdated: Sep 17, 2025
Eligibility criteria

Adults aged 20-55 years. [+4]

History of cervical spine trauma, surgery, or fracture within the past 6 months. [+5]

Status: Recruiting

Neck and Low Back Pain in Medical Students at The University of the West Indies, Mona, Jamaica

The purpose of this study is to identify the prevalence of neck and low back pain in medical students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and to determine the outcome of a standardised spine exercise program on medical students experiencing neck and low back pain, using a prospective randomised control design.

Participants needed: 1,000
Trial details
Biological sex: AllType: InterventionalSponsor: The University of The West IndiesUpdated: Sep 10, 2025Locations: 2
Eligibility criteria

All students enrolled in the medical program at the University of the West Indie... [+2]

Individuals with a history of having spine surgery. [+2]

Status: Not yet recruiting

Effect of Kinesio Tape on Neck Pain in Lactating Women

This study will be conducted to investigate the effect of kinesio tape on neck pain in lactating women.

Participants needed: 60
Trial details
Age: 20-30Biological sex: FemaleType: InterventionalSponsor: Cairo UniversityUpdated: Mar 28, 2025Locations: 1
Eligibility criteria

All women are complaining from neck pain. [+3]

Cervical spondylosis. [+2]

Status: Recruiting

The Effects Of Oculomotor Exercises And Hands-On Protocol In Non-Specific Neck Pain

This study aimed to evaluate the effectiveness of adding oculomotor techniques and hands-on treatments to routine exercise protocols for individuals with non-specific chronic neck pain (NSCNP).

Participants needed: 38
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Yeditepe UniversityUpdated: Nov 4, 2024Locations: 1
Eligibility criteria

The inclusion criteria included being between ages 18 and 65 old, having been di...