Clinical trials

This quasi-experimental study aims to determine the effect of watching an therapeutic video on patients' pain, anxiety, and comfort levels during thyroid biopsy procedures. The study will be conducted in the interventional radiology unit of Muş State Hospital between July 30, 2025, and August 28, 2026. A total of 68 patients (34 experimental and 34 control) will be included. Data will be collected using the Descriptive Information Form, Visual Analog Scale for Pain (VAS-Pain), State Anxiety Inventory, and Visual Analog Scale for Comfort (VAS-Comfort). The intervention group will watch a relaxing video immediately before and during the biopsy procedure, while the control group will receive standard care. Pre- and post-test measurements will be compared to evaluate changes in pain, anxiety, and comfort levels

This randomized controlled trial aims to evaluate the effects of video-assisted early mobilization education on postoperative recovery in patients undergoing laparoscopic cholecystectomy. As part of the intervention, structured and professionally produced educational videos will be used to explain the physiological benefits of early mobilization in the preoperative period and to demonstrate step-by-step mobilization techniques in the postoperative period. Patients in the intervention group will receive video-assisted mobilization education in addition to standard postoperative care, while patients in the control group will receive standard care alone. Physical activity levels will be objectively monitored using wearable activity tracking devices during the first 24 hours after surgery. The study will assess the effects of video-assisted early mobilization education on postoperative physiological stress response, pain, nausea and vomiting, blood glucose levels, mobilization performance, gastrointestinal recovery, length of hospital stay, and patient satisfaction. In addition, postoperative complications, emergency department visits, and hospital readmissions within 30-days after surgery will be evaluated as exploratory outcomes.

This randomized, double-blind, controlled trial aims to investigate the acute effects of therapeutic ultrasound applied to the patellar tendon on vertical jump performance in healthy university students. Therapeutic ultrasound is widely used in physiotherapy to influence soft tissue properties through thermal and mechanical effects; however, its immediate impact on explosive lower-extremity performance and neuromuscular function remains unclear. Participants will be randomly assigned to either a therapeutic ultrasound group or a sham ultrasound (placebo) group. In the intervention group, therapeutic ultrasound will be applied to the patellar tendon using a frequency of 1 MHz and an intensity of 1.5 W/cm² in continuous mode for 5 minutes. In the control group, a sham ultrasound procedure will be performed using the same device and duration without delivering therapeutic energy. Both the participants and the outcome assessor will be blinded to group allocation. Vertical jump performance will be evaluated using the countermovement jump (CMJ) test recorded with the My Jump 2 smartphone application. In addition, quadriceps muscle strength will be measured using a hand-held dynamometer, and knee joint position sense will be assessed using a joint position reproduction test. All measurements will be conducted before and immediately after the intervention. This study will provide evidence regarding whether therapeutic ultrasound applied to the patellar tendon can acutely influence explosive performance, muscle strength, and proprioception in healthy individuals.

In patients who have undergone endotracheal intubation following cardiac surgery, symptoms such as thirst, dysphagia (difficulty swallowing), restlessness, nausea, and vomiting are frequently observed, and these conditions negatively affect the patients' overall comfort. Especially in the post-intubation period, dryness in the mouth and throat, an intense feeling of thirst, and difficulty swallowing can lead to feelings of suffocation, helplessness, fear, and anxiety in patients. Effective management of these symptoms is critically important both for accelerating the recovery process and for increasing patient satisfaction. Traditionally, methods such as moistening the mouth with a cotton swab have been used to relieve complaints like thirst and dry mouth. However, these practices are often insufficient and have limited effectiveness in increasing patients' comfort. In recent years, the use of oropharyngeal sprays has emerged as an innovative and effective approach to alleviate symptoms such as thirst and dry mouth. In a randomized controlled trial conduct, it was shown that a spray-based oropharyngeal moisturizing program significantly reduced the severity of thirst and discomfort in patients who underwent intubation after cardiac surgery. Thirst and discomfort scores were found to be significantly lower in the spray-applied groups compared to the control group, and no significant difference was observed between the groups in terms of dysphagia frequency or adverse events. Similarly, studies conducted in different surgical and intensive care populations have shown that applications of cold water or cold saline sprays significantly reduce complaints of thirst and dry mouth, increase patient comfort, and are safe to use. Additionally, it has been reported that alternative approaches such as menthol lozenges or aromatherapy also have positive effects on thirst, nausea, and comfort after cardiac surgery. Examining the effects of oropharyngeal sprays and similar practices on parameters such as thirst, dysphagia, discomfort, nausea, vomiting, and overall comfort in patients who are intubated after cardiac surgery may contribute to the development of innovative and effective approaches in patient care. Integrating such practices into postoperative care protocols carries significant potential for increasing patient comfort and supporting the recovery process. This randomized controlled study aims to investigate the effects of oropharyngeal humidification after extubation on thirst, pain, and anxiety in patients undergoing coronary artery bypass surgery.

This randomized controlled trial aims to evaluate the effect of a structured self-affirmation intervention on pain, depression, anxiety, and stress levels in patients undergoing mastectomy. The study will be conducted in two parallel groups, with the intervention group listening to an audio recording of positive self-affirmation statements. Primary outcomes will be assessed using the Visual Analog Scale and the Depression Anxiety Stress Scale (DASS-21). The goal is to provide evidence-based strategies to reduce psychosocial burden after mastectomy.

The aim of this study is to evaluate the effects of a solution-focused approach-based individual intervention on psychosocial adjustment and treatment adherence in individuals diagnosed with schizophrenia. The study will be conducted as a randomized controlled trial including 60 clinically stable individuals diagnosed with schizophrenia according to DSM-5 criteria and registered at a Community Mental Health Center affiliated with a university hospital. Participants will be randomly assigned to an experimental group (n=30) and a control group (n=30). The experimental group will receive one individual solution-focused therapy session per week for six weeks. The control group will receive usual care only. Data will be collected using a Personal Information Form, the Psychosocial Adjustment Scale (PSSAS), and the Medication Adherence Scale (MARS).

The middle school period is the period when children begin to experience physical, emotional and social development and try to adapt to psychological changes. In this age group, which is seen as a transition period, the child's academic success and acceptance by peers and friends are also important. The problems experienced during this period can continue in adulthood and children are more likely to experience loneliness, sleep disorders, depression, anxiety, eating disorders, low self-esteem, suicidal thoughts, absenteeism and a decrease in academic success. For this reason, early detection of risky behaviors that threaten children's health and evaluation of health promotion practices are very important issues for child health nursing. In recent years, peer bullying, aggression and social exclusion have increased and continue to increase in the middle school period, also called early adolescence. For this purpose, a study was needed to identify the situation in middle school students and reduce this negativity. In this respect, it is thought that the study will contribute to the literature. In addition, if the hypotheses of the study are confirmed, it is expected that similar training will be provided in other schools and contribute to the reduction of risky behaviors. The aim of this study is to determine the effects of motivational interviewing-based education on peer bullying, social exclusion and aggression in secondary school students and to offer suggestions for situations where deficiencies are observed based on the findings obtained.

In this study titled "Psychological Well-Being and Awareness in the Elderly: The Effect of Reminiscence Therapy", patients will be randomly divided into two groups as experimental and control groups. No intervention will be made to the patients in the control group. Reminiscence therapy will be applied to the patients in the experimental group. Participants will be asked to fill out the scale forms after accepting to participate in the study and obtaining their consent. In addition, after the reminiscence therapy is completed, the experimental and control groups will be asked to fill out the post-test forms. The following questions will be answered in the study; * Does reminiscence therapy affect the psychological well-being levels of the elderly? * Does reminiscence therapy affect the awareness levels of the elderly?

In this study titled "Psycho-Social Effects of Gardening Activities in the Elderly: A Study on Self-Esteem and Life Satisfaction", the elderly will be divided into two groups as experimental and control groups. Participants will be randomly assigned to the groups. No intervention will be made to the patients in the control group. Gardening activities will be performed on the patients in the experimental group as of April. The following questions will be answered in this study; Do gardening activities affect the self-esteem level of the elderly? Do gardening activities affect the life satisfaction level of the elderly?

The purpose of this study is to examine the effect of sleep hygiene education given to heart failure patients on the level of hospital-acquired insomnia of the patients. Participants will be randomly assigned to groups as experimental and control groups. Standard application procedure will be applied to the control group. Sleep hygiene education will be given to the experimental group. Research Hypotheses H0: Sleep hygiene education given to heart failure patients does not have a positive effect on the level of hospital-acquired insomnia of the patients. H1: Sleep hygiene education given to heart failure patients has a positive effect on the level of hospital-acquired insomnia of the patients.

This study will investigate the effect of the FAST HUGS WITH ICU approach on the length of stay in the intensive care unit in patients with hypoxic respiratory failure. Patients will be randomly assigned to the experimental and control groups. The standard procedure will be applied to the control group. The FAST HUGS WITH ICU approach will be applied to the experimental group. We plan to follow up patients with Hypoxic Respiratory Failure using the abbreviation FAST HUGS WITH ICU (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head of bed elevation, Stress Ulcer prophylaxis and Glucose control Spontaneous breathing trial, Water Balance and constipation, Investigation and results, Therapy, Hypo-hyper delirium, Invasive devices, Check the daily infection parameters, Use a checlist). The two groups will be examined in terms of hospital stay and some blood gas parameters.

This is a semi-experimental study. The study aimed to examine the effects of an educational escape game on students' motivation, academic self-efficacy and achievement levels. Students studying in an elderly care program will be included in the study. Students will be divided into 2 groups according to their branches: experimental (educational escape game) and control (question-answer). H1. Students participating in the escape game will show significantly higher motivation in the "Motivation Scale for Teaching Materials" than students participating in the question-answer method. H2. Students participating in the escape game will show significantly higher self-efficacy in the "Academic Self-Efficacy Scale" than students participating in the question-answer method. H3. Students participating in the escape game will show significantly higher success in the "Achievement Test" than students participating in the question-answer method.

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder characterized by chronic recurrent abdominal pain, bloating, changes in bowel habits or bowel movements (1-3). Pharmacological and nonpharmacological methods are used in the treatment of IBS. In addition to lifestyle changes such as dietary changes, physical activity, and stress reduction, relaxation techniques, herbal medicines, and nutritional supplements are important nonpharmacological methods used by IBS patients. Progressive muscle relaxation exercises (PGE) have been reported to positively affect IBS symptoms, patients' quality of life, anxiety, and depression. PGE training in patients with IBS has been found to improve general health perception, reduce symptom severity, and healthcare costs. (7-9). PGE is a complementary treatment and is among advanced nursing practices (10, 11). In this study, a mobile application will be developed to educate patients about IBS and PGE. It is thought that this application will reduce the severity of patients' symptoms and increase their quality of life. This study is planned to determine the effects of mobile technology-based training combined with relaxation exercises on stress, symptom severity and quality of life in patients with irritable bowel syndrome.

This study, examines how maternal education affects caregiving burdens for children with cerebral palsy. Cerebral palsy requires long-term, intensive care, often leading to significant physical, emotional, and financial strain on caregivers. The study aims to assess whether higher maternal education is associated with lower care burdens, possibly due to increased access to resources or coping strategies, and whether lower educational levels result in greater challenges. A survey, combined with standardized measures such as the Caregiver Burden Scale, will be used to quantify the caregiving burden. The results are expected to inform policies or interventions aimed at reducing caregiver strain.

This study aims to investigate the relationship between health literacy, physical activity, back pain, and posture habits among university students. The Health Literacy Scale, the International Physical Activity Questionnaire, and the Posture Habits Questionnaire for Back Health in Daily Activities will be used to collect data from participants. Health literacy will be assessed in terms of individuals' ability to access, understand, and apply health-related information, while physical activity levels and posture habits will be examined for their influence on back pain. The findings are expected to shed light on the role of health literacy in promoting healthier physical activity and posture habits, providing insights for strategies to improve back health in this population.

The aim of this study is to evaluate the effects of deep cervical flexor muscle exercises on pain, spinal posture, and sensory sensitivity in patients with tension-type headaches. Designed as a single-blind randomized controlled trial, the study will assess participants' pain levels using the Visual Analog Scale (VAS), sensory sensitivity through the Sensory Sensitivity Scale, and spinal posture via a digital inclinometer for objective measurements. This research seeks to determine the effectiveness of these exercises in managing pain, improving spinal posture, and contributing to the enhancement of sensory sensitivity.

This study aims to examine the relationships between emotional intelligence, positive social behavior, sleep quality, and academic achievement among students enrolled in health-related academic programs. Specifically, the study will investigate how emotional intelligence levels influence students' social behaviors and academic performance, while also assessing the role of sleep quality in these variables. Data will be collected using the Emotional Intelligence Scale, the Positive Social Behavior Scale, and the Epworth Sleepiness Scale. The findings of this study are expected to provide valuable insights into how emotional intelligence and sleep quality impact students' academic success and social behavior.

This study aims to examine the effects of sujok therapy on pain, fatigue, nausea-vomiting and spiritual well-being levels in patients receiving chemotherapy. The following questions are being answered; * Does sujok therapy affect pain levels in cancer patients? * Does sujok therapy affect fatigue levels in cancer patients? * Does sujok therapy affect nausea-vomiting levels in cancer patients? * Does sujok therapy affect spiritual well-being levels in cancer patients?

The aim of this clinical trial is to determine the effects of su jok seed therapy on pain, anxiety and psychological resilience in patients hospitalized in the oncology ward. This study seeks answers to the following questions; Does su jok seed therapy affect the pain levels of cancer patients? Does su jok seed therapy affect the anxiety levels of cancer patients? Does su jok seed therapy affect the Psychological resilience levels of cancer patients? There will be an experimental and control group in the study and the effectiveness of sujok application will be examined. A total of 8 sessions of su jok seed therapy will be applied to the experimental group, twice a week for a month. No intervention will be made to the control group. Individuals over 18 years old, without communication problems and diagnosed with cancer will be included in the sample.