Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Cast Art for Kids With Extremity Fractures

The goal of this clinical trial is to compare casts with cast art versus those without art in children who sustain a fracture of the extremity. The main goals are: * Determine the difference in satisfaction as measured by the visual analog scale for satisfaction between patients treated in a cast with cast customization versus those in a cast with no cast art * Determine the difference in perceived pain scores between patients treated in a cast with cast customization versus those in a case with no cast art Participants will be randomized to one of three groups: one with plain white cast, one with cast of color wrap of choice, and one with custom cast art. Researchers will compare to see the differences in satisfaction and perception of pain based on what cast the study participant receives.

Participants needed: 96
Trial details
Age: 5-18Biological sex: AllType: InterventionalSponsor: United States Naval Medical Center, PortsmouthUpdated: Oct 9, 2025Locations: 1
Eligibility criteria

Age 5 years old and greater, and less than 18 years old [+3]

Age 18 years old or greater at the time of screening [+2]

Status: Recruiting

Preoperative Use of Pantoprazole for Prevention of Post Operative Nausea and Vomiting in Gynecologic Surgery

The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79. Researchers will compare a placebo to the active medication. Participants will be asked to take three pills around their surgery, two taken before and one taken the night after.

Participants needed: 132
Trial details
Phase: Phase 2Age: 18-79Biological sex: FemaleType: InterventionalSponsor: United States Naval Medical Center, PortsmouthUpdated: May 21, 2025Locations: 1
Eligibility criteria

Undergoing elective gynecological surgery by either an open abdominal or minimal...

Pregnant, [+6]

Status: Recruiting

Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies

Perform a comparison of effective pain relief duration between liposomal bupivacaine and dexmedetomidine when added to bupivacaine in a block for mastectomy for cancer surgery. The erector spinae plane block is a well-established block that is utilized for post operative pain control for procedures performed on the soft tissue of the chest and chest wall as well as intrathoracic procedures. The goal is comparison of the effective duration of both study groups to determine if there is a significant difference in time and amount of post operative opioids required which admitted to hospital.

Participants needed: 200
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: United States Naval Medical Center, PortsmouthUpdated: Nov 19, 2024Locations: 1
Eligibility criteria

Patients requiring any variation of mastectomy with or without axillary lymph no... [+4]

Patient declines a peripheral nerve block. [+9]